It is a demyelinating disease of the central nervous system whose evolution is unpredictable and its effects and symptoms are varied1,2. The data were coded and analysed with the nvivo programme. The clinical course is usually characterized by severe. Thenbergh f, kumpfel t, schumann e, held u, schwan m, blazevic m, et al. Multiple sclerosis main anatomopatological observation is the immunological destruction of myelin1. Multiple sclerosis abstract since more than 100 years carswell, cruveilhier and specially charcot who in 1868 offered the first description about sclerosis in plaques, until today, multiple sclerosis is a challenge to doctors and investigators who treat it. In cuba, a tropical region considered of low prevalence, there are approximately from 550 to 1 650 patients. Multiple sclerosis is an autoimmune disease that affects the central nervous system, most common in young people aged 2050 years. It has a wide clinical spectrum from benign to malignant forms. Medlineplus en espanol tambien contiene enlaces a sitios web no gubernamentales. Informacion en espanol national multiple sclerosis society. In cuba, a tropical region considered of low prevalence, there are. It is the leading cause of disability in this group.
Multiple sclerosis ms is recognized as an inflammatory and neurodegenerative disease of the central nervous system cns 1. Axonal degeneration is thought to be responsible for the irreversible progression of the disability seen in affected patients 2, 3, 4. Descripcion, interpretacion, analisis e importancia del. Aug 23, 2018 please use one of the following formats to cite this article in your essay, paper or report. Expression of metabotropic glutamate receptors in multiple sclerosis brain. The multiple sclerosis patients and family caregivers had different. Multiple sclerosis is an autoimmune, inflammatory and desmyelinization disease of central nervous system cns of unknown etiology and critical evolution. Multiple sclerosis ms is a chronic inflammatory and neurodegenerative disease characterized by focal areas of demyelinationaxonal damage known as plaques. Multiple sclerosis is the major cause of neurological disability in young and middleaged adults. There are different etiological hypotheses talking of a close interrelation among predisposing genetic factors and dissimilar environmental factors, able to give raise to autoimmune response. Serum uric acid levels in multiple sclerosis patients correlate with activity of disease and bloodbrain barrier dysfunction.